What's being depleted
NAD+ runs your cells. Night work depletes it. NMN is the direct precursor your body converts to NAD+. The coenzyme that powers cellular repair on every shift.
One ingredient. 500 mg β‑Nicotinamide Mononucleotide per capsule. Built for the people who don't sleep when everyone else does.
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The dose
Most NMN brands sell 250 mg or hide a smaller dose behind "proprietary blend." The published human trials use 500 mg. That's what's in every Stratus capsule. No half-dose. No filler. No label trick.
The science
What your body is losing. Why sleep can't replace it. What 22 years of data on 74,862 nurses proved.
NAD+ runs your cells. Night work depletes it. NMN is the direct precursor your body converts to NAD+. The coenzyme that powers cellular repair on every shift.
One bottle. One ingredient. The dose the science used. 500 mg of β‑NMN per capsule. No proprietary blend, no eight-extract stack, no filler science chasing the latest study.
Four stages. Each unprotected shift is a withdrawal. BMAL1 breaks. NAMPT shuts down. NAD+ collapses. Damage compounds. Stratus targets the input the cycle starves first.
Built for
By the third night your body is just starting to adapt, and then you rotate off. The recovery days happen in the wrong phase of sleep for the cellular repair work that should be running underneath.
Recover between shifts →Sleep happens in fragments between calls. Every alarm pulls you out of the deeper stages of sleep before they can finish. Those are the stages where cellular repair actually happens.
Replenish what 24 hours depleted →You end up sleeping at the wrong biological time of day more often than the right one, and your cells run on the internal clock, not the local one.
Recover across time zones →You can go from sitting at the station to a full stress response in seconds, several times in a night. That pattern blocks the recovery states that need uninterrupted hours to hold.
Restore what the rotation depletes →Most of your sleep ends up in daylight hours, which is the wrong time for the recovery your body is built around. The schedule and your biology stay out of phase for most of the week.
Replenish what the road depletes →Your body never finishes adapting to one pattern before the next one starts. Sleep length stays the same, but the timing keeps moving. Your cells run on timing, not duration.
Replenish what the rotation depletes →Sleep timing shifts week to week, and the windows where recovery should be running get interrupted before they finish. Years of that compound underneath.
Restore what the watch depletes →A week of nights, a week of evenings, court appearances during what should be sleep, overtime on top. Your body never holds one phase long enough to do the cellular repair that runs on a stable schedule.
Restore what the shift depletes →What to expect
NMN is a multi-week molecule. Here's what shift workers report when they stay on it.
First two weeks, most people feel nothing. The cellular work happens before you can feel it. Most people quit here. Don't.
Your bounce-back gets faster. Three nights doesn't wreck you for four days anymore.
You notice you're sharper at 3 a.m. The fog thins.
Days off feel like days off again. Energy lasts through the rotation, not just the days off.
These are user-reported patterns, not medical claims.
How it works
What's inside
Six things to know about what's in the bottle. And what isn't.
NMN is the direct precursor your body uses to make NAD+. When circadian disruption hits, NAD+ is the molecule that crashes first and recovers last. Replenish the input, and the cellular work that runs on it gets its substrate back.
Human trials on NMN (Mills 2016, Yoshino 2021, Yamaguchi 2024) used doses between 250 mg and 1,000 mg per day, with 500 mg as the most replicated effective dose. Most commercial NMN bottles deliver 250 mg or less. We built Stratus around the dose the science actually tested.
Just β-NMN. No proprietary blends hiding sub-clinical doses. No five-extract synergy stack. Nothing in the bottle except the one molecule the research is actually about.
Every lot tested four ways by independent labs before it ships. Identity, potency, heavy metals, microbials. Certificates of Analysis available on request. Most brands publish one of the four. We publish all four.
Take it daily for 60 days. If it hasn't earned a permanent spot on your nightstand, send back the empty bottle for a full refund. No survey, no return form, no talking to anyone first.
Manufactured entirely in the United States in an FDA-inspected, cGMP-certified facility. Bottle, cap, capsule, label. No outsourced fill. No overseas blend.
Reviews
First month back on a 7-on-7-off and the rebound days don't crater me anymore. Energy on long shifts. Recovery on days off. That's it. That's the review.
Twenty-fours don't ruin the four days after anymore. Sleep when I can. Recover faster when I do. That's all I needed it to do.
Five red-eyes a roster used to mean three days flat at home. Now it costs one. That's the math that matters for me.
The recovery I never got after a busy night started catching up around week six. Fewer chest-tight mornings. Stopped napping at 3 p.m. on off-days.
Same routes. Same hours. Different baseline. Stopped reaching for the second coffee somewhere in week six. That's the only review I have for it.
A week of nights then court at 9 used to flatten me for three days after. Now it's one. Take it or leave it.
From the founder
I built Stratus because no one else was going to. Six time zones a week, red-eyes, rosters that never let your clock settle. I've held a medical certificate through all of it and watched the recovery curve get longer every year.
The research on NAD+ and circadian disruption is twenty years deep. No supplement brand was talking to us. So I made one.
Miles, founder
Pricing
Most shift workers report the difference becomes obvious between weeks 6 and 12.
$47/bottle
$55Save $8
30 days isn't long enough to feel the cellular work. Start here if you want to test the product, not the protocol.
60-day guarantee · Cancel anytime · Free shipping
Consult your physician before starting any new supplement, especially if pregnant, nursing, on medication, or managing a medical condition.
$125/3-pack
$165Save $40
The window where the cellular work actually shows up. Less than the coffee you're using to survive. Per day.
60-day guarantee · Cancel anytime · Free shipping
Consult your physician before starting any new supplement, especially if pregnant, nursing, on medication, or managing a medical condition.
$224/6-pack
$330Save $106
Half a year of cellular work, locked in. For the people who already know NMN works and want to stop reordering.
60-day guarantee · Cancel anytime · Free shipping
Consult your physician before starting any new supplement, especially if pregnant, nursing, on medication, or managing a medical condition.
FAQ
Formulation
500 mg NMN per capsule. Third-party tested. Made in the USA. No proprietary blends.
Stop running on empty
From $37 a bottle. 60-day guarantee. No subscription trap. Made in the USA, tested four ways, built for the people who don't sleep when everyone else does.
P.S. NMN is a multi-week molecule. Give it the full 60 days before deciding whether it earned a permanent place in your routine. If it doesn't, we'll refund every cent. The risk is ours.
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